
Insider and congress filings
Alnylam Pharmaceuticals, Inc. (ALNY)
NASDAQ · Healthcare · 378 insider transactions · 14 congress trades · last filed 20 days agoNasdaq 100
About Alnylam Pharmaceuticals, Inc.
from the company's filings and listing, as of Oct 24, 2026- Exchange
- NASDAQ
- Sector
- Healthcare
- Industry
- Biotechnology
- Chief executive
- Yvonne L. Greenstreet
- Employees
- 2,500
- Listed since
- Jun 1, 2004
- Market value
- $30.0B
- Price to earnings (12 mo)
- 36.7
- Net income per share, as reported (12 mo)
- $6.06
- Dividend yield
- -
Earnings
6 reported quarters · next on Oct 29, 2026| Quarter | EPS | EPS expected | Revenue | Revenue expected | Result |
|---|---|---|---|---|---|
| Q2 FY2026reported Jul 30, 2026 | $1.21 | $1.63 | $1.3B | $1.3B | EPS miss, GAAPRevenue miss |
| Q1 FY2026reported Apr 30, 2026 | $1.51 | $0.87 | $1.2B | $1.1B | EPS beatRevenue beat |
| Q4 FY2025reported Feb 12, 2026 | $0.82 | $1.16 | $1.1B | $1.1B | EPS missRevenue miss |
| Q3 FY2025reported Oct 30, 2025 | $1.84 | $0.56 | $1.2B | $959.4M | EPS beat, GAAPRevenue beat |
| Q2 FY2025reported Jul 31, 2025 | -$0.51 | -$0.54 | $773.7M | $662.9M | EPS beat, GAAPRevenue beat |
| Q1 FY2025reported May 1, 2025 | -$0.44 | -$0.89 | $594.2M | $585.1M | EPS beat, GAAPRevenue beat |
Actual against the consensus estimate at the time. A flag marks a beat or a miss of more than 1.5% either way; inside that band the quarter is in line. A flag marked GAAP compares a GAAP figure the company reported with an adjusted consensus, two different measures, so a one-time gain or charge can move it either way. A flag reads n/a only when a number is missing. Quarterly EPS is the figure set against the consensus, usually adjusted, so the quarters need not add up to the 12-month net income per share above. An estimate is a forecast made by analysts, not a company target.
Executive pay
as filed for fiscal 2025 · proxy filed Apr 6, 2026| Executive | Salary | Stock awards | Other | Total |
|---|---|---|---|---|
| Yvonne L. Greenstreet, M.D.Chief Executive Officer (principal executive officer) | $1.4M | $5.5M | $8.0M | $14.9M |
| Jeffrey V. PoultonExecutive Vice President, Chief Financial Officer (principal financial officer) | $724K | $4.0M | $2.2M | $6.9M |
| Bryan A. SupranExecutive Vice President, Chief Legal Officer and Secretary | $190K | $6.0M | $656K | $6.8M |
| Pushkal Garg, M.D.Executive Vice President, Chief Research and Development Officer | $768K | $3.7M | $2.0M | $6.5M |
| Tolga TangulerExecutive Vice President, Chief Commercial Officer | $698K | $3.7M | $1.7M | $6.1M |
The summary compensation table from the proxy statement for fiscal 2025, with titles as filed then. Executives who have since left are not shown. Read the filing
Institutional holders
13F positions as of Jun 30, 2026| Holder | Value | Shares | Shares vs prior qtr | % of shares out |
|---|---|---|---|---|
| FMR LLC | $4.5B | 15,023,962 | +3.1% | 11.28% |
| Capital World Investors | $3.4B | 11,144,846 | +3.2% | 8.36% |
| BlackRock, Inc. | $3.3B | 10,907,675 | +4.4% | 8.19% |
| Capital Research Global Investors | $2.9B | 9,750,699 | +3.0% | 7.32% |
| Vanguard Portfolio Management LLC | $2.0B | 6,538,390 | +0.7% | 4.91% |
| Vanguard Capital Management LLC | $1.8B | 6,029,478 | +1.4% | 4.53% |
| T. Rowe Price Investment Management, Inc. | $1.7B | 5,642,173 | +8.6% | 4.23% |
| Invesco Ltd. | $1.1B | 3,754,318 | +34.9% | 2.82% |
| State Street Corp | $1.1B | 3,555,689 | +7.0% | 2.68% |
| Geode Capital Management, LLC | $791.3M | 2,635,840 | -0.9% | 1.98% |
| JPMorgan Chase & Co. | $785.3M | 2,675,517 | -57.7% | 2.01% |
| Baillie Gifford & Co | $734.5M | 2,439,889 | -2.2% | 1.83% |
A 13F reports long US equity positions and is filed within 45 days of the quarter end, so these are positions as they stood on Jun 30, 2026. For a manager's whole book see the fund directory. What a 13F covers and leaves out is explained in our guide to Form 13F.
Tracked fund managers holding ALNY
3 managers| Manager | Value | Shares | Share of book |
|---|---|---|---|
| Two Sigma | $564.7M | 1,875,937 | 0.4% |
| Deep Track Capital | $248.3M | 825,000 | 3.6% |
| Paradigm BioCapital | $144.5M | 480,000 | 2.7% |
3 of the 97 fund managers we track list ALNY shares among the largest positions in their latest 13F, filed for Q2 2026. A manager can hold it further down the book too, so this is a floor, not a count. Share of book is the position against the manager's whole disclosed 13F value.
Open-market insider trades
10 filings shown · newest filing first| Insider | Action | Shares | Price | Value | Trade date | Delay (business days) |
|---|---|---|---|---|---|---|
| Bryan SupranEVP, CLO and Secretary | Sold | 1,758 | $226.88 | $399K | Oct 2, 2026filed Oct 6, 2026 | 2d |
| David E. I. PyottDirector | Sold · scheduled · 5 lines | 3,830 | $299.18 | $1.1M | Jun 1, 2026filed Jun 3, 2026 | 2d |
| Melissa McLaughlinChief Human Resources Officer | Sold · scheduled · 5 lines | 2,286 | $330.42 | $755K | Apr 6, 2026filed Apr 7, 2026 | 1d |
| Melissa McLaughlinChief Human Resources Officer | Sold · scheduled · 9 lines | 1,624 | $319.59 | $519K | Apr 2, 2026filed Apr 7, 2026 | 3d |
| Kevin Joseph FitzgeraldCSO & EVP, Head of Research | Sold · scheduled · 4 lines | 658 | $323.98 | $213K | Mar 5, 2026filed Mar 6, 2026 | 1d |
| Kevin Joseph FitzgeraldCSO & EVP, Head of Research | Sold · scheduled · 8 lines | 633 | $323.08 | $205K | Mar 4, 2026filed Mar 6, 2026 | 2d |
| Tolga TangulerEVP, Chief Commercial Officer | Sold · 8 lines | 2,309 | $323.08 | $746K | Mar 4, 2026filed Mar 6, 2026 | 2d |
| Jeffrey V. PoultonEVP, Chief Financial Officer | Sold · 8 lines | 2,468 | $323.08 | $797K | Mar 4, 2026filed Mar 6, 2026 | 2d |
| Yvonne GreenstreetChief Executive Officer | Sold · 8 lines | 2,933 | $323.08 | $948K | Mar 4, 2026filed Mar 6, 2026 | 2d |
| Pushkal GargEVP Chief R&D | Sold · scheduled | 500 | $326.08 | $163K | Mar 5, 2026filed Mar 6, 2026 | 1d |
One row is one filing, newest filing first. A filing that reported its trade in several tranches is summed, priced at the weighted average, and marked with its line count. Scheduled: set up in advance under a Rule 10b5-1 trading plan. The delay counts business days from the trade to the filing, the unit of Form 4's two business day deadline: weekends and federal holidays are skipped. How the filing itself works is explained in our guide to Form 4.
Other Form 4 activity (14)
| Insider | Event | Shares | Date |
|---|---|---|---|
| Yvonne GreenstreetChief Executive Officer | Stock award | 107 | Sep 19, 2026 |
| Benjamin CravattDirector | Stock award | 4,393 | Jun 1, 2026 |
| David E. I. PyottDirector | Option exercise | 3,830 | Jun 1, 2026 |
| Stuart A. ArbuckleDirector | Stock award | 2,112 | May 20, 2026 |
| Dennis A. AusielloDirector | Stock award | 2,112 | May 20, 2026 |
| Olivier BrandicourtDirector | Stock award | 2,112 | May 20, 2026 |
| Margaret A. HamburgDirector | Stock award | 2,112 | May 20, 2026 |
| Peter N. KelloggDirector | Stock award | 2,112 | May 20, 2026 |
| David E. I. PyottDirector | Stock award | 2,112 | May 20, 2026 |
| Colleen F. ReitanDirector | Stock award | 2,112 | May 20, 2026 |
| Amy W. SchulmanDirector | Stock award | 2,640 | May 20, 2026 |
| Charles Elliott SigalDirector | Stock award | 2,112 | May 20, 2026 |
| Amy W. SchulmanDirector | Option exercise | 11,250 | May 13, 2026 |
| Melissa McLaughlinChief Human Resources Officer | Other Form 4 entry (see filing) | 3,567 | Mar 25, 2026 |
Awards, option exercises, shares withheld to cover tax and gifts all file on the same form as a purchase or a sale. None of them is a decision to trade, so they sit here rather than beside the ones that are.
Congress trades in ALNY
14 disclosures of 14 on record · median 29d of the 45 allowedSince the trade: the stock's move from the trade date to the latest close we hold (figures as of Oct 24, 2026), not the member's result. Not investment advice.
| Member | Type | Action | Amount disclosed | Stock since the trade | Trade date | Disclosed | Delay |
|---|---|---|---|---|---|---|---|
| Cory A. BookerSpouse | Stock | Sale (Full) | $1,001 - $15,000 | +1.3%After the saleS&P 500 -1.4% · +2.7 pts vs S&P 500 | Aug 11, 2026 | Sep 9, 2026 | 29d |
| Jefferson Shreve | Stock | Sale | $15,001 - $50,000 | -17.1%After the saleS&P 500 +30.4% · -47.4 pts vs S&P 500 | May 12, 2025 | Jun 22, 2025 | 41d |
| Josh GottheimerJoint | Stock | Purchase | $1,001 - $15,000 | +14.8%S&P 500 +59.6% · -44.7 pts vs S&P 500 | Jan 11, 2024 | Feb 15, 2024 | 35d |
| Josh GottheimerJoint | Stock | Sale | $1,001 - $15,000 | +23.8%After the saleS&P 500 +54.7% · -30.9 pts vs S&P 500 | Jan 29, 2024 | Feb 15, 2024 | 17d |
| Josh GottheimerJoint | Stock | Sale | $1,001 - $15,000 | +31.1%After the saleS&P 500 +64.5% · -33.5 pts vs S&P 500 | Dec 11, 2023 | Jan 7, 2024 | 27d |
| Daniel S. Goldman | Stock | Purchase | $15,001 - $50,000 | +12.2%S&P 500 +87.9% · -75.7 pts vs S&P 500 | Mar 6, 2023 | Apr 17, 2023 | 42d |
| Daniel S. Goldman | Stock | Sale | $15,001 and uptop of band not in our data | -1.0%After the saleS&P 500 +87.1% · -88.1 pts vs S&P 500 | Jan 31, 2023 | Feb 24, 2023 | 24d |
| Ro Khanna | Stock | Exchange | $1,001 - $15,000 | -3.8%S&P 500 +98.2% · -102.0 pts vs S&P 500 | Jan 4, 2023 | Jan 6, 2023 | 2d |
| Josh GottheimerJoint | Stock | Purchase | $1,001 - $15,000 | +6.3%S&P 500 +105.2% · -98.9 pts vs S&P 500 | Sep 28, 2022 | Oct 16, 2022 | 18d |
| Josh GottheimerJoint | Stock | Sale | $1,001 - $15,000 | +65.3%After the saleS&P 500 +112.3% · -47.0 pts vs S&P 500 | Nov 13, 2020 | Dec 9, 2020 | 26d |
| Josh GottheimerJoint | Stock | Purchase | $1,001 - $15,000 | +99.8%S&P 500 +186.9% · -87.1 pts vs S&P 500 | Apr 6, 2020 | May 13, 2020 | 37d |
| Ro Khanna | Stock | Purchase | $1,001 - $15,000 | +235.0%S&P 500 +177.1% · +57.9 pts vs S&P 500 | Jun 3, 2019 | Jul 11, 2019 | 38d |
| Josh GottheimerJoint | Stock | Sale | $1,001 - $15,000 | +185.1%After the saleS&P 500 +175.0% · +10.1 pts vs S&P 500 | Oct 18, 2018 | Nov 16, 2018 | 29d |
| Josh GottheimerJoint | Stock | Purchase | $1,001 - $15,000 | +122.6%S&P 500 +177.9% · -55.3 pts vs S&P 500 | Jun 1, 2018 | Oct 2, 2018 | 123d |
Since the trade is an estimate, set beside the S&P 500 over the same window, with the gap between the two in percentage points. The filing carries a band, not a fill, and a sale keeps the stock's sign, so a positive figure after a sale means the stock kept rising after it. An option row carries the underlying stock's move. A row marked n/a is one we hold no figure for.
A delay above 45 days is the gap between the dates on the report; we mark a filing late only after checking it.
"Not captured" means the band or the transaction type on the original report is missing from our data.
"Dates conflict" marks a row whose disclosure is dated before its trade on the record we hold. Both dates are printed as filed, and no since-the-trade figure is computed from them.
Every Congress trade in ALNY, filterable by party, chamber, type and account.
Members of Congress reporting a position
1 member · estimate, as of Oct 23, 20261 member reports a position (estimated). The largest estimated position is in the $1,001 - $15,000 band.
| Member | Party, chamber | Estimated position | Share of their portfolio |
|---|---|---|---|
| Lucy McBath | Democrat · House | $1,001 - $15,000 | 0.1% |
Estimate, as of Oct 23, 2026. Each position is modelled from the member's disclosed transactions and annual filings: the midpoint of each disclosed band, moved with the stock's price since the trade. It is a rough estimate of a reported position, not a figure from a filing, which is why it is shown as a band. Share of portfolio sets that estimate against the member's whole estimated public-stock portfolio.
Questions
Are insiders buying or selling ALNY?
Across the 10 most recent open-market filings shown here, 0 were purchases and 10 were sales. 6 were scheduled in advance under a Rule 10b5-1 plan.
Which members of Congress have traded ALNY?
Cory A. Booker, Jefferson Shreve, Josh Gottheimer, Daniel S. Goldman and Ro Khanna disclosed ALNY transactions in the filings shown here.
Which members of Congress hold ALNY?
1 member of Congress reports a position in ALNY in the estimate we hold as of Oct 23, 2026. The estimated position belongs to Lucy McBath. The estimate is built from disclosed transactions and annual filings, so it is shown as a band rather than a figure from a filing.
Is ALNY in the S&P 500 or the Nasdaq 100?
Alnylam Pharmaceuticals, Inc. is a current member of the Nasdaq 100, per the membership list we hold as of Oct 26, 2026. Current members of either index get a page here whatever their filing history.
How quickly are ALNY trades disclosed?
Insider filings on this page reached the public a median of 2 business days after the transaction (weekends and federal holidays skipped), against the two business days Form 4 allows. Congressional disclosures took a median of 29 days, against the 45 the STOCK Act allows.
How to read a Form 4
A DECISION THE INSIDER MADE
COMPENSATION PLUMBING
Congress rows disclose a value range rather than an exact amount, and the STOCK Act allows up to 45 days to report. Full sourcing and the limits of this data are on the methodology page. A filing is a record of a transaction, not a signal, and nothing here is investment advice.
Data as of Oct 26, 2026.
