Earnings call briefSecond-quarter 2026

Merck says it expects U.S. Keytruda growth to moderate as it nears peak penetration

Merck said it expects the approximately $250 million benefit from wholesaler purchase timing in the third quarter of 2025 not to repeat this year.

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On its second-quarter call, Merck said it expects total U.S. Keytruda year-over-year growth to moderate as it increasingly reaches peak penetration across several key indications.

Merck also said it expects third-quarter OHTUVAYRE sales to be affected by the unwind of second-quarter specialty pharmacy purchases. It said it expects these actions to lead to accelerated OHTUVAYRE growth in 2027.

Quotes from the call

“...we anticipate that total U.S. KEYTRUDA year-over-year growth will moderate as we increasingly reach peak penetration across several key indications.”

Caroline Litchfield, Chief Financial Officer

Key facts from the call

Expected U.S. Keytruda year-over-year growth
To moderate as peak penetration is increasingly reached
Expected non-repeat of third-quarter 2025 wholesaler timing benefit
Approximately $250 million
Expected third-quarter OHTUVAYRE sales
Affected by unwind of second-quarter specialty pharmacy purchases

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Source: Merck's second-quarter 2026 earnings call, August 4, 2026.

Written by GetSignal with AI from the company's earnings call.

Not investment advice.

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