Earnings call briefThird-quarter 2026

Vertex Pharmaceuticals lifts 2026 non-GAAP expense outlook to about $6 billion

The company attributes the increase to about $250 million of Crinetics operating and integration costs, with standalone spending at the high end of the prior range.

GetSignal Vertex Pharmaceuticals VRTX

Vertex Pharmaceuticals said on its third-quarter call it now expects combined non-GAAP operating expenses of approximately $6 billion for 2026, up from $5.65 billion to $5.75 billion.

The company also expects total nonoperating costs of $105 million for 2026 related to the financing of Crinetics. Vertex Pharmaceuticals said interest income is projected to be approximately $60 million lower than it otherwise would have been.

Quotes from the call

“On operating expenses, we are revising our prior combined non GAAP operating expense guidance of $5.65 billion to $5.75 billion to a revised estimate of approximately $6 billion.”

Charles F. Wagner Jr., Chief Operating Officer and Chief Financial Officer

Key facts from the call

2026 non-GAAP operating expense outlook
Approximately $6 billion, up from $5.65 billion to $5.75 billion
Crinetics operating and integration costs in outlook
Approximately $250 million
2026 nonoperating costs outlook
$105 million, related to the financing of Crinetics
Interest income outlook
Approximately $60 million lower than it otherwise would have been, due to lower cash balances after the acquisition

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Source: Vertex Pharmaceuticals' third-quarter 2026 earnings call, November 2, 2026.

Written by GetSignal with AI from the company's earnings call.

Not investment advice.

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